Beautiful day scientist uses skin cell to make " kind embryonic dry cell "-

Beautiful day scientist uses skin cell to make " kind embryonic dry cell "

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The group of 3 independent scientific research that comes from the United States and Japan said on June 6, they succeeded to make the common skin cell of experimental rat the cell that has function of embryonic dry cell.

If this one experiment can succeed in the experiment on human body, will evasive long-term since the politics that uses an issue around human embryo and ethics argue, because this is considered as a of domain of dry cell research major breakthrough.

Be modelled on embryonic dry cell

Be in early last year, japan thes capital of a country Yamanaka did the Shinya 　 of the university to study relevantly. He discovers, a kind of as dry as embryo cell much can the 4 gene combine related the gender guides when cell of small rat-tail ministry is medium, these cells can have the quality that is similar to embryonic dry cell.

And part by Shinya 　 Yamanaka, 3 when Jienixi and the Kanglade Huoqielinge that breath out Buddha university lead the · of rash path husband that Masschusetts Institute of Technology conceives institute of medicine of being of especially black heart newest, serve as a foundation with afore-mentioned discovery namely and try to improve. Relevant research already was published as a result in " natural " of magazine and new start publication " cellular · does a cell " on magazine website.

The cell of skin of one seed coat that the principle that experiments this is a mice " fiber former cell " undertake departing gradually, reach finally new cellular form. They use carrier of a kind of ultravirus, 4 kinds of transcribe child gene carbon, namely Oct4, sox2, c - Myc, it is normal to guide with Klf4 inside small rat cell. Because weigh group of rate to have one thousandth only, so researcher needs the cell of eliminate no use.

Those are singled out recombine a cell to be called " by revulsive much can the gender does a cell " (IPS cell) . The IPS cell function that after these improvement, gets does a cell with embryo almost same, can split up the constituent cell of different type.

For test and verify this, researcher labelled with fluorescent dye IPS cell, and their infuse in the inchoate brilliant embryo of small rat, result discovery, these brilliant embryo can succeed development is normal small rat, wh some of which is whole even the IPS cell that the body is existing to derive.

Evasive ethics controversy

Embryonic dry cell is known as " all-purpose cell " , but all the time since, get human body embryo to do a cell to must destroy embryo, this suffer censure quite. American president Bush prevents the proposed law that uses federal fund at this kind of research again and again.

Scientific group hopes to find a kind of method all the time, the gene of cell of will common human body weaves afresh, make its have dry cell function, avoid completely to use embryo. If human cell is such, such gimmick may bring about breakthrough of great medical treatment, do not involve the moral dispute that use embryo causes not only, and because the cell is come from,accept put oneself in another's position, after so the patient accepted the organ of place implantation, will not appear repellent phenomenon.

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2007-8-15 18:15:59